Objective To explore the contamination characteristics of furan in commercially infant formula and supplementary food and assess the health risk of furan exposure among Chinese infant population. Methods Based on the convenience sampling method, 260 commercial infant formula and supplementary food were collected in Beijing, Zhejiang, Shandong, and Sichuan from 2017 to 2018. Furan was determined by isotope dilution headspace-gas chromatography-mass spectrometry method. Probabilistic assessment method was adopted to assess the risk of furan exposure in infants aged 0 to 36 months from 2015 infant food consumption survey data. Results The detection rate of furan in infant formula and supplementary food was 90.32%-100.00%, and the average contamination level was 4.05-46.26 μg/kg. The average contamination level of furan in meat puree was the highest (46.26 μg/kg), followed by vegetable puree (41.31 μg/kg), and the lowest was infant formula (4.05 μg/kg). The average exposure of furan in infants aged 0-36 months was 21.95 ng/kg BW. Infants aged 0-36 months were divided into three groups:0-6 months, 7-12 months and 13-36 months. The exposure of furan was the highest in infants aged 7-12 months. Considering non-neoplastic effects of furan, the range of margin of exposure (MOE) value for each group was 651-3 936. Considering neoplastic effects of furan, the range of MOE value for each group was 13 322-80 566. Conclusion For the infants aged 0-36 months and high consumers, the health risk of furan exposure from infant formula and supplementary food was of low concern.