2018—2020年天津市津南区食源性致病菌分布及药敏分析
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(天津市津南区疾病预防控制中心,天津 300350)

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孙雅娜 女 主管检验师 研究方向为肠道致病菌病原检测和药敏分析 E-mail:synsyn.happy@163.com

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津南区哨点医院食源性疾病腹泻病例阳性菌株药敏分析(20190101)


Distribution and drug sensitivity analysis of foodborne pathogens in Jinnan District of Tianjin from 2018 to 2020
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(Center for Disease Control and Prevention of Jinnan District, Tianjin 300350, China)

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    摘要:

    目的 对2018—2020年天津市津南区食源性致病菌污染进行监测及耐药分析,了解天津市津南区食源性疾病流行病学特征和耐药情况,为预防和控制食源性疾病提供依据。方法 对2018—2020年津南区哨点医院607例食源性疾病粪便标本进行沙门菌、致泻大肠埃希菌、副溶血性弧菌和志贺菌4种致病菌检测,并对阳性菌株做药敏分析。结果 607例粪便标本中共检出阳性菌株124株,阳性检出率20.43%(124/607)。其中沙门菌74株,副溶血性弧菌31株,致泻大肠埃希菌19株,未检出志贺菌。患者中,男∶女为4∶3(347/260);沙门菌中肠炎沙门菌检出率最高,达62.16%(46/74),致泻大肠埃希菌中肠致病性大肠埃希菌(EPEC)检出率最高;药物敏感试验中,沙门菌和致泻大肠埃希菌对氨苄西林(AMP)耐药显著,高达72.04%(67/93),且普遍存在多重耐药情况,副溶血性弧菌对头孢唑啉(CFZ)的耐药最严重[77.42%(24/31)]。结论 天津市津南区2018—2020年引起腹泻的食源性疾病致病菌以肠炎沙门菌、EPEC为主。分离菌株普遍对AMP耐药,且存在多重耐药情况,提示相关部门应加强对食品加工业的监管,同时加强致病菌耐药的监测力度,为津南区食品安全和临床治疗提供依据。

    Abstract:

    Objective To investigate the epidemiological characteristics and drug resistance of foodborne diseases in Jinnan District by monitoring and drug resistance analysis of foodborne diseases from 2018 to 2020, so as to provide basis for prevention and control of foodborne diseases. Methods The stool samples of 607 cases of foodborne diseases in sentinel hospitals of Jinnan District from 2018 to 2020 were detected for Salmonella, diarrheogenic Escherichia coli, Vibrio parahaemolyticus and Shigella, and the drug sensitivity of positive strains was analyzed. Results A total of 124 positive strains were detected in 607 stool samples, with a positive detection rate of 20.43% (124/607). There were 74 strains of Salmonella, 31 strains of Vibrio parahaemolyticus, 19 strains of diarrheogenic Escherichia coli, and no Shigella was detected. The ratio of male to female was 4∶3 (347/260). The highest detection rate in Salmonella was Salmonella enteritidis(62.16%, 46/74), and the highest detection rate in diarrheogenic Escherichia coli was enteropathogenic Escherichia coli (EPEC). In drug sensitivity test, Salmonella and diarrheogenic Escherichia coli were significantly resistant to ampicillin (AMP), up to 72.04% (67/93), and multiple drug resistance was common. Vibrio parahaemolyticus was most resistant to cefazolin (CFZ) (77.42%, 24/31). Conclusion Salmonella enteritidis and EPEC are the main pathogens of foodborne diseases in Jinnan District of Tianjin from 2018 to 2020. Strains are resistant to AMP with multi-drug resistance. It suggested that the relevant departments should strengthen the supervision of food processing industry, and strengthen the monitoring of drug resistance of pathogenic bacteria, so as to provide the basis for food safety and clinical treatment in Jinnan District.

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孙雅娜,刘坚龄,梁广忠,李胜强,李龙玉,郑梅,杨勇,柯慧.2018—2020年天津市津南区食源性致病菌分布及药敏分析[J].中国食品卫生杂志,2021,33(5):548-552.

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  • 收稿日期:2021-07-21
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  • 在线发布日期: 2021-10-14
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