Abstract:pice oleoresins were extracted by Soxhlet extractor and their antioxidationeffect were studied with linoleic acid bubble oxidizing method.Results indicated that their antioxidation presents dose-effect relationship and the antimutagenicityof Lilac,Crevost,Nutmeg,Fennel,Anise and White Pepper are evident,andLilac have the most powerful antimutagenicity. Lour, Bay,Almend andXanthoxylum have mutagenicity.Statistieal analysis showed the possibility thatthere may be a connectionbetween antioxidation and antimutagenicity of thespices.Author's address Hong Dongxu,Nutrition Section of 208 Hospital ChangchunCity,Jilin 130062,PRC