The effects of compounds of edible fugus polysccharides(CEFP) i.e. hericium erinaceus, lentinus edodes and poria cocos with equal ratio, with procyanidins oligomers and glycyrrhetinicacid with certain ratio on mice T cell supressed by tumour and CP was observed. The results showed that the percentage of L 3T 4, lyt-2 and L 3T 4/lyt-2 in S-180 group dropped signficently, which were improved by CEFP and sacchardes lentinus edodes and the CEFP group recovered to normal control. It also showed that CP decreased the ratio of L 3T 4/lyt-2 and the L 3T 4 level, but had no effects on lyt-2. It was found that therapy effects of CP on tumor mice was effective except for its immunity inhibition. CEFP and sacchardes lentinus edodes could resist the negative effects of CP significantly and had concord effects. CEFP effects were better than that of sacchardes lentinus edodes only, which showed the importance of the compounds of antitumor effective substance. Author's address Liu Changxi, Institute of Food Safety Control and Inspection, Ministry of Health, Beijing 100021 PRC.