Cordyceps-preparation was administrated to mice by dose of 0 064 g/kg,0 132 g /kg,0 4 g/kg BW to assess the Cordyceps-preparation's effect on both the mice immune function and glycometabolism.;;By the dose of 0 4 g/kg,the Cordyceps-preparation could improve the mice humor al immunity,cellular immunity,macrophagocyte and NK cell immune function.In the normal animal and the hyperglycemia animal model induced by alloxan,the Cordycep s-preparation could improve the sugar tolerance,but it had no effect on the fas ting glucose in normal animal. Author's address: Shanghai Center of Disease Prevention And Control, 200336 PRC.