Objective To explore the key points of management on foods added with probiotics. Methods A questionnaire survey was conducted to investigate the main production enterprises of selling foods added with probiotics in Chinese markets. Analysing and comparing the data from FAO/WHO, IDF, EU, USA, Japan and China on the management of foods added with probiotics. Results Probiotics were mainly added in milk powder, yoghourt and health food, etc., but the information on labels about probiotics were not coherent. The regulations for foods added with probiotics were diversified in different countries. Conclusion The foods added with probiotics are in ascending in food markets. The safe use and standard management of probiotics in foods are hot points in the field of food safety. The key points on the management of foods added with probiotics are: unifying and standardizing the concept of probiotics, assessing requirements and programs, taking good manufacture practice, labeling and after-market supervising.