Objective To establish and implement HACCP in breeding and production of Spirulina for health food products.Methods Analyzing the hazards in the process of breeding and producing Spirulina,identifying critical control points and improving the corresponding control measures according to GB/T 27341—2009 Hazard analysis and critical control point(HACCP) system-General requirements for food processing plant and GB/T 16919—1997 Edible Spirulina powder.Results HACCP for breeding and production of Spirulina was set up and implemented,good results were obtained,and the problems in the establishment of HACCP were discussed.Conclusion Implementing HACCP is an ongoing process,constant development and complement in practice is needed.