To monitor the concentration and distribution of estrogens-like compounds (ECs) in fresh food purchased in Changsha City and provide fundamental database for the pollutant traceability as well as its hazard control.Methods Abided by stratified sampling method, 172 food samples were purchased randomly from markets. Bisphenol A (BPA), nonyl phenol (NP), ethinyloestradiol (EE₂) and estradiol (E₂) levels in food was detected by LC-MS/MS method, and the concentration relationship between different ECs compounds was analyzed by spearman correlation test. In addition, the tendency of ECs occurring in food categories was explored by correspondence analysis. Results ECs existed in all samples more or less and presented NP>BPA>E₂>EE₂ in detection rate. Moreover, the Spearman correlation test and correspondence analysis revealed BPA was low but positively associated with NP and EE₂ in content.Conclusion Concentration of selected ECs component in food is considerably below limitation, however, the co-existence of multiple ECs may enlarge their health effects.