杭州市居民发酵类食品中氨基甲酸乙酯的暴露评估
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(杭州市疾病预防控制中心,浙江 杭州 310021)

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王玲莉 女 主管医师 研究方向为食品安全风险监测和评估 E-mail:hzcdcwll@163.com

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杭州市科技局社会发展科研专项(20120433B02)


Exposure assessment for Hangzhou residents to ethyl carbamate from fermented foods
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(Hangzhou Center for Disease Prevention and Control,Zhejiang Hangzhou 310021,China)

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    摘要:

    通过分析杭州市主要发酵类食品中氨基甲酸乙酯含量及居民食物消费量,评估杭州市居民膳食中氨基甲酸乙酯暴露水平及其潜在风险。方法 利用2014年杭州市居民发酵类食物消费量数据,以及在杭州市采集的373份食品样品的检测结果,获得杭州市居民膳食中氨基甲酸乙酯的摄入量,利用点估计法对居民由膳食摄入的氨基甲酸乙酯进行风险评估。结果 共检测食品样品373份,检出含氨基甲酸乙酯样品160份,总检出率为42.9%,其中黄酒检出率为100.0%(37/37),其次为南乳、药酒、土烧及白酒,检出率均超过80%,而发酵面制品、发酵乳制品、发酵豆制品(除腐乳)、发酵茶饮料、啤酒及醋中氨基甲酸乙酯含量均低于检出限。按照食物消费量的均值估算,杭州市居民每日氨基甲酸乙酯平均暴露量为0.076 4 μg/kg BW,总暴露限值(MOE)为3 932;根据食品化学物高端暴露模型计算,杭州市居民氨基甲酸乙酯高暴露人群每天摄入量为0.309 3 μg/kg BW,MOE为970。结论 杭州市居民膳食中氨基甲酸乙酯的平均暴露水平已经超过公共卫生关注度界点,尤其是氨基甲酸乙酯高暴露人群,存在较高健康风险,应对这部分人群予以高度关注。

    Abstract:

    To analyze the ethyl carbamate level in fermented foods and the dietary intake of residents in Hangzhou, and to assess the risk.Methods Based on the data of fermented food consumption and the results of 373 food samples collected in Hangzhou in 2014, the residents' intake of ethyl carbamate was obtained. The risk of dietary intake of ethyl carbamate was assessed. Results Ethyl carbamate was detected in 160 of 373 samples(42.9%) from 8 categories of food. Yellow wine samples were all positive and the detection rates of fermented red beancurd, white spirit, medicinal wine, cooking wine were all above 80%. The levels of ethyl carbamate in fermented flour products, fermented dairy products, fermented bean products (except preserved beancurd), fermented tea, beer and vinegar were all below the detection limit. In accordance with the mean value of food consumption estimates, the average ethyl carbamate exposure of Hangzhou residents from fermented foods were 0.076 4 μg/kg BW per day and the margin of exposure (MOE) value was 3 932. The high exposure in Hangzhou residents were 0.309 3 μg/kg BW per day and the MOE value was 970.Conclusion The average dietary ethyl carbamate exposure of Hangzhou residents from fermented foods exceeded the point of a public health concern, and more attention should be paid to the consumers with high exposure to ethyl carbamate.

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王玲莉,黄春萍,陈树昶.杭州市居民发酵类食品中氨基甲酸乙酯的暴露评估[J].中国食品卫生杂志,2017,29(1):105-109.

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  • 收稿日期:2016-10-24
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  • 在线发布日期: 2017-03-15
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