A simple method employing mass spectrum for identification and photodiode array detector for determination was established for the analysis of sildenafil and cialis in health food. The separation was carried on a reverse phase C 18 column with two mobile phase system. Good linearity between peak areas and analyte concentrations was obtained with relative coefficient better than 0.999. The recoveries for sildenafil and cialis were 96.9% and 97.7% respectively. The developed method was quite sensitive,precise,and showed good reproducibility.