The qualitative and quantitative analysis and drug resistance test for Listeria Monocytogenes in 155 samples of raw meat, meat products and sea foods from Quanzhou market were carried out in the period from Dec. 2000 to Dec. 2001 in an attempt to find out the food contamination status by Listeria Monocytogenes in Quanzhou, Fujian Province. The overall positive detection rate for Listeria was 35.8% ( raw meat 68.12%, sea foods 12.5% and processed meat products 6.52%) and for Listeria Monocytogenes was 3.87% (raw meat 8.7% and not detected in sea foods and processed meat products). Six strains of Listeria Monocytogenes were highly sensitive to ampicillin, cefoxintin, ofloxacin. penicillin G, tetracycline and vacomycin; moderate sensitive to ciprofloxacin and resistant to nitrofurantoin. It is recommended that the relevant authorities develop appropriate control measures promptly to strengthen monitoring and prevent the outbreak of food poisoning caused by Listeria Monocytogenes.