Objective The aim of the survey is to secure fast-food safety and prevent food-borne diseases in the Chinese Export Commodities Fair of Guangzhou (CECF). Methods\ The hygienic administration system of HACCP (Hazard analysis and critical control point) was employed in the course of prepared-food processing,combining with food-hygiene supervisors stationing and inspecting on the spot of the fast-food street during the fair period. Applications for entering into CECF fast-food street from every food-preparing unit were strictly censored,even the ranges and varieties of fast or prepared food were also rigidly examined. Raw material purchasing,food processing and serving were defined as the critical points and corresponding control-measures for each critical point were established. Results\ The sanitary qualification rates of fast-food in the CECF have been remarkably elevated after applying HACCP. Furthermore,the hygienic and legal awareness,as well as the sanitary knowledge level of food-workers have been greatly strengthened. No new complaints on food sanitation or food-borne disease occurred from then on. Conclusions This kind of managing mode on food supply,having the characteristics of tremendous effectiveness and practicability to ensure food sanitation and safety,is worth further generalization in other important large-scale and short-period public activities.