To help the acidophilus milk manufacturers to establish a HACCP system, our research work focused on the feasibility and efficiency of the HACCP system in such factories. In terms of the principles and procedures of HACCP system and guideline for its application recommended by CAC and in reference to the regulations and standards on GMP, SSOP and HACCP home and abroad, we made the research in a pilot factory. On the basis of the hazard analysis on raw materials, product's inner quality, process design and technology, staff, package and transportation and according to the severity and probability of the hazard, we defined the obvious hazard and the CCP on the producing line. This article did not made parts of whole HACCP analysis and meant only for reference in the field.