食物中吡咯里西啶生物碱污染水平、检测技术及风险评估研究现状
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1.成都医学院;2.中国测试技术研究院生物研究所

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四川省科技厅重点研发项目(2023YFS0398)食品中多种新污染物精准检测关键技术体系研究及预警应用;四川省科技厅重点研发项目(2024YFFK0429)基于15N同位素示踪法探究多酚阻断香肠中亚硝胺生成的构效机制;成都市重点研发支撑计划项目(2022-YF05-00994-SN)茶叶中氯酸盐等污染物检测关键技术与风险评估研究;中国测试技术研究院“人才计划”项目(RC202407)食品重要标准物质研制及现场快检仪器量值溯源关键技术研究;


Pyrrolizidine alkaloid contamination in food: current research on levels, detection techniques, and risk assessment
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1. Chengdu Medical College;2. Institute of Biological Technology, National Institute of Measurement and Testing Technology

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    摘要:

    吡咯里西啶类生物碱(PAs)是一类存在于植物中的天然有毒化合物,能够通过食物链传播和富集,在全球均有分布,目前在茶叶、蜂蜜、谷物等多种食品以及中草药中均有检出。研究表明,PAs的污染水平存在地区和种间差异,目前部分地区食品中PAs含量已超过安全标准,对生命健康造成潜在威胁。常用的分析方法包括:薄层色谱法、气相色谱-质谱联用、液相色谱-质谱联用等,本文旨在探讨食物中PAs的污染水平、检测技术及风险评估的研究现状。总体而言,PAs的相关研究取得了一定进展,但仍需加强对其污染机制、长期暴露风险及更有效检测方法的探索。

    Abstract:

    Pyrrolizidine alkaloids (PAs) are a kind of natural toxic compounds existing in plants, which can be spread and enriched through the food chain, and are distributed all over the world. At present, they are detected in tea, honey, cereals and other foods as well as Chinese herbs. Studies have shown that there are regional and interspecific differences in PAs contamination levels, and PAs content in food in some areas has exceeded the safety standard, posing a potential threat to life and health. Common analytical methods include thin layer chromatography, gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, etc. This paper aims to discuss the pollution level, detection technology and risk assessment of PAs in food. Overall, some progress has been made in the study of PAs, but there is still a need to strengthen the exploration of its pollution mechanism, long-term exposure risk, and more effective detection methods.

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  • 收稿日期:2024-12-03
  • 最后修改日期:2025-04-26
  • 录用日期:2025-04-27
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