Objective To find out the contamination of aquatic products from vibrio parahaemolyticus in Guangzhou city, and to provide reference basis for assessing the safety of aquatic products. Methods Aquatic products were collected quarterly from caterings, fishery markets, wholesale markets and supermarkets for testing vibrio parahemolyticus. Results A total of 102/753 aquatic product samples isolated for vibrio parahaemolyticus were positive (13.55%). The detection rate was significantly different in different species (χ²=13.106，P < 0.05), in different years(χ²=55.583，P < 0.05) and from different sampling sites( χ²=14.268，P < 0.05,). Conclusion The detection rate of vibrio parahaemolyticus in aquatic products in Guangzhou was high, it might be one of potential risks for foodborn diseases.